Chemical Tools for Targeted Amplification of Reactive Oxygen Species in Neutrophils

Chemical Tools for Targeted Amplification of Reactive Oxygen Species in Neutrophils

A number of chemical compounds are known, which amplify the availability of reactive oxygen species (ROS) in neutrophils both in vitro and in vivo. They can be roughly classified into NADPH oxidase 2 (NOX2)-dependent and NOX2-independent reagents. NOX2 activation is triggered by protein kinase C ago...

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Bibliographic Details
Main Authors: Viktor Reshetnikov, Jonas Hahn, Christian Maueröder, Christine Czegley, Luis Enrique Munoz, Martin Herrmann, Markus H. Hoffmann, Andriy Mokhir
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
aminoferrocenes
autoimmune disease
chronic granulomatous disease
inflammation
NADPH oxidase 2
neutrophils
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01827/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01827/full

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