Genetic Predisposition to Alzheimer’s Disease Is Associated with Enlargement of Perivascular Spaces in Centrum Semiovale Region

Genetic Predisposition to Alzheimer’s Disease Is Associated with Enlargement of Perivascular Spaces in Centrum Semiovale Region

This study investigated whether genetic factors involved in Alzheimer’s disease (AD) are associated with enlargement of Perivascular Spaces (ePVS) in the brain. A total of 680 participants with T2-weighted MRI scans and genetic information were acquired from the ALFA study. ePVS in the basal ganglia...

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Bibliographic Details
Main Authors: Iacopo Ciampa, Grégory Operto, Carles Falcon, Carolina Minguillon, Manuel Castro de Moura, David Piñeyro, Manel Esteller, Jose Luis Molinuevo, Roderic Guigó, Arcadi Navarro, Juan Domingo Gispert, Natalia Vilor-Tejedor, for the ALFA Study
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Genes
Subjects:
<i>APOE</i>-<i>ε4</i>
<i>BIN1</i>-rs744373
enlargement of perivascular spaces
neurogenetics
virchow robin spaces
Online Access:https://www.mdpi.com/2073-4425/12/6/825

Internet

https://www.mdpi.com/2073-4425/12/6/825

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