Serotonin-promoted elevation of ROS levels may lead to cardiac pathologies in diabetic rat

Serotonin-promoted elevation of ROS levels may lead to cardiac pathologies in diabetic rat

Patients with diabetes mellitus (DM) develop tendencies toward heart disease. Hyperglycemia induces the release of serotonin from enterochromaffin cells (EC). Serotonin was observed to elevate reactive oxygen species (ROS) and downregulate antioxidant enzymes. As a result, elevated levels o...

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Bibliographic Details
Main Authors: Ali Tahir, Shaheen Farhat, Mahmud Madiha, Waheed Hina, Ishtiaq Muhammad, Javed Qamar, Murtaza Iram
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2015-01-01
Series:Archives of Biological Sciences
Subjects:
serotonin
ROS
catalase
SOD
diabetes and cardiac hypertrophy
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2015/0354-46641500028A.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2015/0354-46641500028A.pdf

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