STINGing the Tumor Microenvironment to Promote Therapeutic Tertiary Lymphoid Structure Development

STINGing the Tumor Microenvironment to Promote Therapeutic Tertiary Lymphoid Structure Development

Tertiary lymphoid structures (TLS), also known as ectopic lymphoid structures (ELS) or tertiary lymphoid organs (TLO), represent a unique subset of lymphoid tissues noted for their architectural similarity to lymph nodes, but which conditionally form in peripheral tissues in a milieu of sustained in...

Full description

Bibliographic Details
Main Authors: Jessica N. Filderman, Mark Appleman, Manoj Chelvanambi, Jennifer L. Taylor, Walter J. Storkus
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
immunotherapy
STING agonists
tertiary lymphoid structures
T cells
tumor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.690105/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.690105/full

Similar Items