Imatinib resistance: diagnostic and therapeutic choices
We report a case of a 42-year-old woman with t(9;22) positive chronic myeloid leukemia (CML) who developed a sub-optimal response to therapy with imatinib mesylate due to M351T mutation and low plasma level of imatinib. Dose increase of imatinib resulted in toxicity. She obtained a complete molecula...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
SEEd
2015-10-01
|
Series: | Clinical Management Issues |
Subjects: | |
Online Access: | https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1073 |