Imatinib resistance: diagnostic and therapeutic choices

We report a case of a 42-year-old woman with t(9;22) positive chronic myeloid leukemia (CML) who developed a sub-optimal response to therapy with imatinib mesylate due to M351T mutation and low plasma level of imatinib. Dose increase of imatinib resulted in toxicity. She obtained a complete molecula...

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Bibliographic Details
Main Authors: Marianna De Muro, Odoardo Maria Olimpieri, Rosa Greco, Lidia Altomare
Format: Article
Language:English
Published: SEEd 2015-10-01
Series:Clinical Management Issues
Subjects:
Online Access:https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1073