Uptake and activation of eicosapentaenoic acid are related to accumulation of triacylglycerol in Ramos cells dying from apoptosis

The present study investigates the mechanism behind induction of cell death by eicosapentaenoic acid (EPA) in leukemia cells. The PUFA-sensitive cell lines Raji and Ramos, which die by necrosis and apoptosis upon incubation with EPA respectively, had 2- to 3-fold higher uptake rate of EPA than the P...

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Bibliographic Details
Main Authors: Hanne S. Finstad, Hanne Dyrendal, Mari C. Wik Myhrstad, Hilde Heimli, Christian A. Drevon
Format: Article
Language:English
Published: Elsevier 2000-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324032