Uptake and activation of eicosapentaenoic acid are related to accumulation of triacylglycerol in Ramos cells dying from apoptosis
The present study investigates the mechanism behind induction of cell death by eicosapentaenoic acid (EPA) in leukemia cells. The PUFA-sensitive cell lines Raji and Ramos, which die by necrosis and apoptosis upon incubation with EPA respectively, had 2- to 3-fold higher uptake rate of EPA than the P...
Main Authors: | Hanne S. Finstad, Hanne Dyrendal, Mari C. Wik Myhrstad, Hilde Heimli, Christian A. Drevon |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2000-04-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520324032 |
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