Immunoprotectivity of HLA-A2 CTL peptides derived from respiratory syncytial virus fusion protein in HLA-A2 transgenic mouse.

Identification of HLA-restricted CD8+ T cell epitopes is important to study RSV-induced immunity and illness. We algorithmically analyzed the sequence of the fusion protein (F) of respiratory syncytial virus (RSV) and generated synthetic peptides that can potentially bind to HLA-A*0201. Four out of...

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Bibliographic Details
Main Authors: Hsiao-Yun Shao, Yi-Wen Lin, Shu-Ling Yu, Hsiang-Yin Lin, Ebenezer Chitra, Yung-Chen Chang, Charles Sia, Pele Chong, Ming-Tao Hsu, Olivia L Wei, Yen-Hung Chow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3183052?pdf=render