Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments
<p>Abstract</p> <p>Background</p> <p>Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, divergences and tools, and further how this variation impacts speci...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2006-08-01
|
Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/7/376 |