CS2164 and Venetoclax Show Synergistic Antitumoral Activities in High Grade B-Cell Lymphomas With MYC and BCL2 Rearrangements

CS2164 and Venetoclax Show Synergistic Antitumoral Activities in High Grade B-Cell Lymphomas With MYC and BCL2 Rearrangements

High-grade B-cell lymphoma with concurrent MYC and BCL2 rearrangements (HGBL-DHL) is a rare, aggressive mature B-cell malignancy with a high likelihood of treatment failure following front-line immunochemotherapies. Patients with HGBL-DHL who develop a relapsed or refractory disease have little effe...

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Bibliographic Details
Main Authors: Delin Yuan, Genhong Li, Lian Yu, Yuelong Jiang, Yuanfei Shi, Qiulin Chen, Xiaomei Ma, Lan V. Pham, Ken H. Young, Manman Deng, Zhihong Fang, Bing Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
HGBL-DHL
MYC
BCL2
CS2164
venetoclax
synergy/synergism
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.618908/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.618908/full

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