The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome

The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome

Mitochondrial dysfunction seems to play a key role in the etiology of insulin resistance. At birth, a link has already been established between mitochondrial DNA (mtDNA) content and insulin levels in cord blood. In this study, we explore shared epigenetic mechanisms of the association between mtDNA...

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Bibliographic Details
Main Authors: Brigitte Reimann, Bram G. Janssen, Rossella Alfano, Akram Ghantous, Almudena Espín-Pérez, Theo M. de Kok, Nelly D. Saenen, Bianca Cox, Oliver Robinson, Marc Chadeau-Hyam, Joris Penders, Zdenko Herceg, Paolo Vineis, Tim S. Nawrot, Michelle Plusquin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
insulin
mitochondrial DNA content
epigenome-wide methylation
cord blood insulin levels
mitochondrial dysfunction
differentially methylated regions
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00325/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00325/full

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