Poxvirus antigen staining of immune cells as a biomarker to predict disease outcome in monkeypox and cowpox virus infection in non-human primates.

Poxvirus antigen staining of immune cells as a biomarker to predict disease outcome in monkeypox and cowpox virus infection in non-human primates.

Infection of non-human primates (NHPs) such as rhesus and cynomolgus macaques with monkeypox virus (MPXV) or cowpox virus (CPXV) serve as models to study poxvirus pathogenesis and to evaluate vaccines and anti-orthopox therapeutics. Intravenous inoculation of macaques with high dose of MPXV (>1-2...

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Bibliographic Details
Main Authors: Haifeng Song, Krisztina Janosko, Reed F Johnson, Jing Qin, Nicole Josleyn, Catherine Jett, Russell Byrum, Marisa St Claire, Julie Dyall, Joseph E Blaney, Gerald Jennings, Peter B Jahrling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618230?pdf=render

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http://europepmc.org/articles/PMC3618230?pdf=render

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