HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane.

The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the release of diverse retroviruses from human, but not monkey, cells and is thought to do so by ablating a dominant restriction to particle release. Here, we determined how Vpu expression affects the subcellular di...

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Bibliographic Details
Main Authors: Stuart J D Neil, Scott W Eastman, Nolwenn Jouvenet, Paul D Bieniasz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0020039