Intravitreal S100B Injection Leads to Progressive Glaucoma Like Damage in Retina and Optic Nerve

Intravitreal S100B Injection Leads to Progressive Glaucoma Like Damage in Retina and Optic Nerve

The glial protein S100B, which belongs to a calcium binding protein family, is up-regulated in neurological diseases, like multiple sclerosis or glaucoma. In previous studies, S100B immunization led to retinal ganglion cell (RGC) loss in an experimental autoimmune glaucoma (EAG) model. Now, the dire...

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Bibliographic Details
Main Authors: Sandra Kuehn, Wilhelm Meißner, Pia Grotegut, Carsten Theiss, H. Burkhard Dick, Stephanie C. Joachim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
glaucoma
animal model
S100B protein
retinal ganglion cell damage
optic nerve degeneration
electroretinogram
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00312/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00312/full

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