Unique Allelic eQTL Clusters in Human MHC Haplotypes

The control of gene regulation within the major histocompatibility complex (MHC) remains poorly understood, despite several expression quantitative trait loci (eQTL) studies revealing an association of MHC gene expression with independent tag-single nucleotide polymorphisms (SNPs). MHC haplotype var...

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Bibliographic Details
Main Authors: Tze Hau Lam, Meixin Shen, Matthew Zirui Tay, Ee Chee Ren
Format: Article
Language:English
Published: Oxford University Press 2017-08-01
Series:G3: Genes, Genomes, Genetics
Subjects:
MHC
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.043828