RANK (TNFRSF11A) Is Epigenetically Inactivated and Induces Apoptosis in Gliomas

RANK (TNFRSF11A) Is Epigenetically Inactivated and Induces Apoptosis in Gliomas

Alterations of DNA methylation play an important role in gliomas. In a genome-wide screen, we identified a CpG-rich fragment within the 5′ region of the tumor necrosis factor receptor superfamily, member 11A gene (TNFRSF11A) that showed de novo methylation in gliomas. TNFRSF11A, also known as recep...

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Bibliographic Details
Main Authors: Anna von dem Knesebeck, Jörg Felsberg, Anke Waha, Wolfgang Hartmann, Björn Scheffler, Martin Glas, Jennifer Hammes, Thomas Mikeska, Pearlly S. Yan, Elmar Endl, Matthias Simon, Guido Reifenberger, Torsten Pietsch, Andreas Waha
Format: Article
Language:English
Published: Elsevier 2012-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612801084

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http://www.sciencedirect.com/science/article/pii/S1476558612801084

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