Determination of pyrazinamide in human by high performance liquid chromatography.

Determination of pyrazinamide in human by high performance liquid chromatography.

A facile and sensitive high performance liquid chromatographic (HPLC) technique has been developed for the determination pyrazinamide (PZA) in human plasma. Nicotinamide(NIA) is used as internal standard(IS). Plasma is deproteinized with 0.7 M perchloric acid; clear supernatant is neutralized with 1...

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Bibliographic Details
Main Authors: Revankar S, Desai N, Vaidya A, Bhatt A, Anjaneyulu B
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 1994-01-01
Series:Journal of Postgraduate Medicine
Subjects:
Adult
Antitubercular Agents
blood
Biological Availability
Chromatography
High Pressure Liquid
methods
standards
Human
Male
Niacinamide
Pyrazinamide
pharmacokinetics
Reproducibility of Results
Online Access:http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1994;volume=40;issue=1;spage=7;epage=9;aulast=Revankar

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http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1994;volume=40;issue=1;spage=7;epage=9;aulast=Revankar

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