Biological stoichiometry in human cancer.

A growing tumor in the body can be considered a complex ecological and evolutionary system. A new eco-evolutionary hypothesis (the "Growth Rate Hypothesis", GRH) proposes that tumors have elevated phosphorus (P) demands due to increased allocation to P-rich nucleic acids, especially riboso...

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Bibliographic Details
Main Authors: James J Elser, Marcia M Kyle, Marilyn S Smith, John D Nagy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2000353?pdf=render