Nox2 Upregulation and p38α MAPK Activation in Right Ventricular Hypertrophy of Rats Exposed to Long-Term Chronic Intermittent Hypobaric Hypoxia

Nox2 Upregulation and p38α MAPK Activation in Right Ventricular Hypertrophy of Rats Exposed to Long-Term Chronic Intermittent Hypobaric Hypoxia

One of the consequences of high altitude (hypobaric hypoxia) exposure is the development of right ventricular hypertrophy (RVH). One particular type of exposure is long-term chronic intermittent hypobaric hypoxia (CIH); the molecular alterations in RVH in this particular condition are less known. St...

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Bibliographic Details
Main Authors: Eduardo Pena, Patricia Siques, Julio Brito, Silvia M. Arribas, Rainer Böger, Juliane Hannemann, Fabiola León-Velarde, M. Carmen González, M. Rosario López, Ángel Luis López de Pablo
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
high altitude
cardiac hypertrophy
kinases and NADPH oxidase
Online Access:https://www.mdpi.com/1422-0067/21/22/8576

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https://www.mdpi.com/1422-0067/21/22/8576

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