Germ cell nuclear factor regulates gametogenesis in developing gonads.

Germ cell nuclear factor regulates gametogenesis in developing gonads.

Expression of germ cell nuclear factor (GCNF; Nr6a1), an orphan member of the nuclear receptor gene family of transcription factors, during gastrulation and neurulation is critical for normal embryogenesis in mice. Gcnf represses the expression of the POU-domain transcription factor Oct4 (Pou5f1) du...

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Bibliographic Details
Main Authors: Davood Sabour, Xueping Xu, Arthur C K Chung, Damien Le Menuet, Kinarm Ko, Natalia Tapia, Marcos J Araúzo-Bravo, Luca Gentile, Boris Greber, Karin Hübner, Vittorio Sebastiano, Guangming Wu, Hans R Schöler, Austin J Cooney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4139263?pdf=render

Internet

http://europepmc.org/articles/PMC4139263?pdf=render

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