The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

Summary: Apolipoprotein M (apoM) is the carrier of sphingosine-1-phosphate (S1P) in plasma high-density lipoproteins. S1P is a bioactive lipid interacting with five receptors (S1P1–5). We show that lack of apoM in mice increases the amount of brown adipose tissue (BAT), accelerates the clearance of...

Full description

Bibliographic Details
Main Authors: Christina Christoffersen, Christine K. Federspiel, Anna Borup, Pernille M. Christensen, Andreas N. Madsen, Markus Heine, Carsten H. Nielsen, Andreas Kjaer, Birgitte Holst, Joerg Heeren, Lars B. Nielsen
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717318387

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717318387

Similar Items