Heterogeneous trajectory of depressive symptoms after repeated subcutaneous esketamine injections

Heterogeneous trajectory of depressive symptoms after repeated subcutaneous esketamine injections

Background: Ketamine is an effective antidepressant with a 65–70% response rate and a fast onset of action. Esketamine (S-ketamine) has been found to be twice as potent as R-ketamine, while inducing fewer adverse effects, such as sedation and cognitive impairment, than racemic ketamine. However, lit...

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Main Authors: Matheus Ghossain Barbosa, Luciana Maria Sarin, Marco Aurélio Tuena, Lorena Catarina Del Sant, Carolina Nakahira, Eduardo Jorge Muniz Magalhães, Victor Augusto Rodovalho Fava, Rodrigo Simonini Delfino, Matheus Souza Steglich, Camila Puertas, Ana Cecília Lucchese, Juliana Canada Surjan, Guilherme Lozi Abdo, Hugo Cogo-Moreira, José Alberto Del Porto, Acioly Luiz Tavares de Lacerda, Andrea Parolin Jackowski
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Affective Disorders Reports
Subjects:
Esketamine
Depression
Injections, subcutaneous
Models
Statistical
Online Access:http://www.sciencedirect.com/science/article/pii/S2666915320300536

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http://www.sciencedirect.com/science/article/pii/S2666915320300536

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