Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila

Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila

Class IV ddaC neurons specifically prune larval dendrites without affecting axons during Drosophila metamorphosis. ddaCs distribute the minus ends of microtubules (MTs) to dendrites but the plus ends to axons. However, a requirement of MT minus-end-binding proteins in dendrite-specific pruning remai...

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Bibliographic Details
Main Authors: Yan Wang, Menglong Rui, Quan Tang, Shufeng Bu, Fengwei Yu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
microtubule orientation
minus end
dendrite
neuron
dendrite morphology
pruning
Online Access:https://elifesciences.org/articles/39964

Internet

https://elifesciences.org/articles/39964

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