A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis

A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis

Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by an important heterogeneity, reflected by different clinical outcomes and chemoresistance. During carcinogenesis, tumor cells display aberrant glycosylated structures, synthetized by deregulated glycosyltransferases, supporting t...

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Bibliographic Details
Main Authors: Yousra Mohamed Abd-El-Halim, Abdessamad El Kaoutari, Françoise Silvy, Marion Rubis, Martin Bigonnet, Julie Roques, Jérôme Cros, Rémy Nicolle, Juan Iovanna, Nelson Dusetti, Eric Mas
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:EBioMedicine
Subjects:
Glyco-signature
Glycosyltransferases
Pancreatic ductal adenocarcinoma
Prognosis
Tumor stratification
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003340

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http://www.sciencedirect.com/science/article/pii/S2352396421003340

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