Silvestrol Inhibits Chikungunya Virus Replication

Silvestrol, a natural compound that is isolated from plants of the genus <i>Aglaia</i>, is a specific inhibitor of the RNA helicase eIF4A, which unwinds RNA secondary structures in 5&#8242;-untranslated regions (UTRs) of mRNAs and allows translation. Silvestrol has a broad antiviral...

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Bibliographic Details
Main Authors: Lisa Henss, Tatjana Scholz, Arnold Grünweller, Barbara S. Schnierle
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/10/11/592