Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data

Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data

Abstract Background Genome-wide association studies (GWAS) have identified several hundred susceptibility loci for type 2 diabetes (T2D). One critical, but unresolved, issue concerns the extent to which the mechanisms through which these diverse signals influencing T2D predisposition converge on a l...

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Main Authors: Juan Fernández-Tajes, Kyle J. Gaulton, Martijn van de Bunt, Jason Torres, Matthias Thurner, Anubha Mahajan, Anna L. Gloyn, Kasper Lage, Mark I. McCarthy
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-019-0628-8

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