Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex

Dengue virus (DENV) is the most common arboviral infection globally, infecting an estimated 390 million people each year. We employed a genome-wide clustered regularly interspaced short palindromic repeat (CRISPR) screen to identify host dependency factors required for DENV propagation and identifie...

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Bibliographic Details
Main Authors: David L. Lin, Natalia A. Cherepanova, Leonia Bozzacco, Margaret R. MacDonald, Reid Gilmore, Andrew W. Tai, W. Ian Lipkin
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/4/e00939-17