The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus

The Lysine Deacetylase RpdA Is Essential for Virulence in Aspergillus fumigatus

Current suboptimal treatment options of invasive fungal infections and emerging resistance of the corresponding pathogens urge the need for alternative therapy strategies and require the identification of novel antifungal targets. Aspergillus fumigatus is the most common airborne opportunistic mold...

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Bibliographic Details
Main Authors: Ingo Bauer, Matthias Misslinger, Yana Shadkchan, Anna-Maria Dietl, Verena Petzer, Thomas Orasch, Beate Abt, Stefan Graessle, Nir Osherov, Hubertus Haas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Microbiology
Subjects:
KDAC
RpdA
murine virulence model
Aspergillus fumigatus
xylose
xylP
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02773/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02773/full

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