The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling.

BACKGROUND: CCL21 acting through CCR7, is termed a homeostatic chemokine. Based on its role in concerting immunological responses and its proposed involvement in tissue remodeling, we hypothesized that this chemokine could play a role in myocardial remodeling during left ventricular (LV) pressure ov...

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Bibliographic Details
Main Authors: Alexandra Vanessa Finsen, Thor Ueland, Ivar Sjaastad, Trine Ranheim, Mohammed S Ahmed, Christen P Dahl, Erik T Askevold, Svend Aakhus, Cathrine Husberg, Arnt E Fiane, Martin Lipp, Lars Gullestad, Geir Christensen, Pål Aukrust, Arne Yndestad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4232360?pdf=render