Transcriptomic analysis identifies organ-specific metastasis genes and pathways across different primary sites

Abstract Background Metastasis is the most devastating stage of cancer progression and often shows a preference for specific organs. Methods To reveal the mechanisms underlying organ-specific metastasis, we systematically analyzed gene expression profiles for three common metastasis sites across all...

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Bibliographic Details
Main Authors: Lin Zhang, Ming Fan, Francesco Napolitano, Xin Gao, Ying Xu, Lihua Li
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-020-02696-z