A new in vivo screening paradigm to accelerate antimalarial drug discovery.

A new in vivo screening paradigm to accelerate antimalarial drug discovery.

The emergence of resistance to available antimalarials requires the urgent development of new medicines. The recent disclosure of several thousand compounds active in vitro against the erythrocyte stage of Plasmodium falciparum has been a major breakthrough, though converting these hits into new med...

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Bibliographic Details
Main Authors: María Belén Jiménez-Díaz, Sara Viera, Javier Ibáñez, Teresa Mulet, Noemí Magán-Marchal, Helen Garuti, Vanessa Gómez, Lorena Cortés-Gil, Antonio Martínez, Santiago Ferrer, María Teresa Fraile, Félix Calderón, Esther Fernández, Leonard D Shultz, Didier Leroy, David M Wilson, José Francisco García-Bustos, Francisco Javier Gamo, Iñigo Angulo-Barturen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3692522?pdf=render

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http://europepmc.org/articles/PMC3692522?pdf=render

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