Ca2+ sensor synaptotagmin-1 mediates exocytosis in mammalian photoreceptors

Ca2+ sensor synaptotagmin-1 mediates exocytosis in mammalian photoreceptors

To encode light-dependent changes in membrane potential, rod and cone photoreceptors utilize synaptic ribbons to sustain continuous exocytosis while making rapid, fine adjustments to release rate. Release kinetics are shaped by vesicle delivery down ribbons and by properties of exocytotic Ca2+ senso...

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Bibliographic Details
Main Authors: Justin J Grassmeyer, Asia L Cahill, Cassandra L Hays, Cody Barta, Rolen M Quadros, Channabasavaiah B Gurumurthy, Wallace B Thoreson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
retina
ribbon synapse
rods
cones
exocytosis
electroretinogram
Online Access:https://elifesciences.org/articles/45946

Internet

https://elifesciences.org/articles/45946

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