Controlling the outcome of the Toll-like receptor signaling pathways.

The Toll-Like Receptors (TLRs) are proteins involved in the immune system that increase cytokine levels when triggered. While cytokines coordinate the response to infection, they appear to be detrimental to the host when reaching too high levels. Several studies have shown that the deletion of speci...

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Bibliographic Details
Main Authors: Guilhem Richard, Calin Belta, A Agung Julius, Salomon Amar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282698?pdf=render