DNA Damage and Repair Biomarkers in Cervical Cancer Patients Treated with Neoadjuvant Chemotherapy: An Exploratory Analysis.

DNA Damage and Repair Biomarkers in Cervical Cancer Patients Treated with Neoadjuvant Chemotherapy: An Exploratory Analysis.

Cervical cancer cells commonly harbour a defective G1/S checkpoint owing to the interaction of viral oncoproteins with p53 and retinoblastoma protein. The activation of the G2/M checkpoint may thus become essential for protecting cancer cells from genotoxic insults, such as chemotherapy. In 52 cervi...

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Bibliographic Details
Main Authors: Patrizia Vici, Simonetta Buglioni, Domenico Sergi, Laura Pizzuti, Luigi Di Lauro, Barbara Antoniani, Francesca Sperati, Irene Terrenato, Mariantonia Carosi, Teresa Gamucci, Rosanna Dattilo, Monica Bartucci, Cristina Vincenzoni, Luciano Mariani, Enrico Vizza, Giuseppe Sanguineti, Angiolo Gadducci, Ilio Vitale, Maddalena Barba, Ruggero De Maria, Marcella Mottolese, Marcello Maugeri-Saccà
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4773222?pdf=render

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http://europepmc.org/articles/PMC4773222?pdf=render

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