HOXA5 inhibits metastasis via regulating cytoskeletal remodelling and associates with prolonged survival in non-small-cell lung carcinoma.

Homeobox genes comprise a family of regulatory genes that contain a common homeobox domain and act as transcription factors. Recent studies indicate that homeobox A5 (HOXA5) may serve as a tumour suppressor gene in breast cancers. However, the precise role and the underlying mechanism of HOXA5 in lu...

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Main Authors: Chi-Chung Wang, Kang-Yi Su, Hsuan-Yu Chen, So-Yi Chang, Chi-Fan Shen, Chia-Hung Hsieh, Qi-Sheng Hong, Ching-Cheng Chiang, Gee-Chen Chang, Sung-Liang Yu, Jeremy J W Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4396855?pdf=render