Resistance Mutations A30K and Y93N Associated with Treatment Failure with Sofosbuvir and Daclatasvir for Hepatitis C Virus Infection Non-Responder Patients: Case Reports

In Brazil, hepatitis C treatment has been evolving significantly with the licensing of direct-acting antivirals (DAAs). However, viral determinants (amino acid substitutions in hepatitis C virus (HCV) genome and infective genotype) associated with host factors (hepatic condition and prior HCV therap...

Full description

Bibliographic Details
Main Authors: Vanessa D. Costa, Patricia Pellegrini, Vivian Rotman, Ana Maria Pittella, Estevão P. Nunes, Barbara V. Lago, Elisabeth Lampe, Francisco C. A. Mello
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Viruses
Subjects:
daa
Online Access:https://www.mdpi.com/1999-4915/11/11/1004