Sleep deprivation changes thimet oligopeptidase (THOP1) expression and activity in rat brain

The consequences of sleep deprivation on memory, cognition, nociception, stress, and endocrine function are related to the balance of neuropeptides, with peptidases being particularly essential. Thimet oligopeptidase (THOP1) is a metallopeptidase implicated in the metabolism of many sleep-related pe...

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Bibliographic Details
Main Authors: Bruna Visniauskas, Priscila S.R. Simões, Fernanda M. Dalio, Maria D.G. Naffah-Mazzacoratti, Vitor Oliveira, Sergio Tufik, Jair R. Chagas
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019365557