Structure Identification of ViceninII Extracted from Dendrobium officinale and the Reversal of TGF-β1-Induced Epithelial–Mesenchymal Transition in Lung Adenocarcinoma Cells through TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways

Structure Identification of ViceninII Extracted from Dendrobium officinale and the Reversal of TGF-β1-Induced Epithelial–Mesenchymal Transition in Lung Adenocarcinoma Cells through TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways

ViceninII is a naturally flavonoid glycoside extracted from Dendrobium officinale, a precious Chinese traditional herb, has been proven to be valuable for cancer treatment. Transforming growth factor-β1 (TGF-β1), promotes the induction of epithelial–mesenchymal transition...

Full description

Bibliographic Details
Main Authors: Yingyi Luo, Zhiyao Ren, Biaoyan Du, Shangping Xing, Shaowei Huang, Yunrong Li, Zhouxi Lei, Dan Li, Huanhuan Chen, Yuechun Huang, Gang Wei
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
Dendrobium officinale
ViceninII
structural identification
EMT
TGF-β/Smad
PI3K/Akt/mTOR
lung adenocarcinoma
A549
H1299 cells
Online Access:http://www.mdpi.com/1420-3049/24/1/144

Internet

http://www.mdpi.com/1420-3049/24/1/144

Similar Items