Increased Level of IFN-γ and IL-4 Spot-Forming Cells on ELISPOT Assay as Biomarkers for Acute Graft-Versus-Host Disease and Concurrent Infections

Acute graft-versus-host disease (aGVHD) remains a significant cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Infections may coexist and in certain circumstances aggravate aGVHD. It was described that type 1 as well as type 2 cytokines are important mediato...

Full description

Bibliographic Details
Main Authors: Yoshihiro Komada, Eiichi Azuma, Masahiro Hirayama
Format: Article
Language:English
Published: MDPI AG 2012-04-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/1/2/61