Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain

<p>Abstract</p> <p>Background</p> <p>In human carcinomas, overexpression of cortactin correlates with poor prognosis. Cortactin is an F-actin-binding protein involved in cytoskeletal rearrangements and cell migration by promoting actin-related protein (Arp)2/3 mediated...

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Bibliographic Details
Main Authors: Seggelen Vera, Schuuring-Scholtes Ellen, van Rossum Agnes GSH, Kluin Philip M, Schuuring Ed
Format: Article
Language:English
Published: BMC 2005-02-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/6/15