Tuning the reactivity of alkoxyl radicals from 1,5-hydrogen atom transfer to 1,2-silyl transfer

Tuning the reactivity of alkoxyl radicals from 1,5-hydrogen atom transfer to 1,2-silyl transfer

The generation of α-carbon radicals from alkoxyl radicals is challenging because 1,2-hydrogen atom transfer (HAT) is usually less favoured than 1,5-HAT. Here, the authors report a strategy to inhibit 1,5-HAT by introducing a silyl group into the α-position of alkoxyl radicals, enabling preparation o...

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Bibliographic Details
Main Authors: Zhaoliang Yang, Yunhong Niu, Xiaoqian He, Suo Chen, Shanshan Liu, Zhengyu Li, Xiang Chen, Yunxiao Zhang, Yu Lan, Xiao Shen
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22382-y

Internet

https://doi.org/10.1038/s41467-021-22382-y

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