Quantifying Gene Essentiality Based on the Context of Cellular Components

Different genes have their protein products localized in various subcellular compartments. The diversity in protein localization may serve as a gene characteristic, revealing gene essentiality from a subcellular perspective. To measure this diversity, we introduced a Subcellular Diversity Index (SDI...

Full description

Bibliographic Details
Main Authors: Kaiwen Jia, Yuan Zhou, Qinghua Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01342/full