Striatal dopamine synthesis capacity in autism spectrum disorder and its relation with social defeat: an [18F]-FDOPA PET/CT study

Abstract Alterations in dopamine signalling have been implied in autism spectrum disorder (ASD), and these could be associated with the risk of developing a psychotic disorder in ASD adults. Negative social experiences and feelings of social defeat might result in an increase in dopamine functioning...

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Bibliographic Details
Main Authors: Rik Schalbroeck, Floris H. P. van Velden, Lioe-Fee de Geus-Oei, Maqsood Yaqub, Therese van Amelsvoort, Jan Booij, Jean-Paul Selten
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01174-w