Indole-3-carbinol induces apoptosis of chronic myelogenous leukemia cells through suppression of STAT5 and Akt signaling pathways
Signal transducer and activator of transcription 5 and Akt pathways, implicated in signaling transduction downstream of BCR–ABL, play critical roles in the pathogenesis of chronic myeloid leukemia. Therefore, identification of novel compounds that modulate the activity of such pathways could be a ne...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IOS Press
2017-05-01
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| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428317705768 |