Influence of Intermittent Cold Stimulations on CREB and Its Targeting Genes in Muscle: Investigations into Molecular Mechanisms of Local Cryotherapy

Influence of Intermittent Cold Stimulations on CREB and Its Targeting Genes in Muscle: Investigations into Molecular Mechanisms of Local Cryotherapy

Local cryotherapy is widely used as a treatment for sports-related skeletal muscle injuries. The molecular mechanisms are unknown. To clarify these mechanisms, we applied one to three 15-min cold stimulations at 4 °C to various cell lines (in vitro), the tibialis anterior (TA) muscle (ex vivo), and...

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Bibliographic Details
Main Authors: Takehito Sugasawa, Yoshiya Tome, Yoshinori Takeuchi, Yasuko Yoshida, Naoya Yahagi, Rahul Sharma, Yuichi Aita, Haruna Ueda, Reina Maruyama, Kaoru Takeuchi, Shohei Morita, Yasushi Kawamai, Kazuhiro Takekoshi
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
CREB
cryotherapy
gene expression
icing
mitochondria
Pgc-1α
Online Access:https://www.mdpi.com/1422-0067/21/13/4588

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https://www.mdpi.com/1422-0067/21/13/4588

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