Regulation of Fibrotic Processes in the Liver by ADAM Proteases

Fibrosis in the liver is mainly associated with the activation of hepatic stellate cells (HSCs). Both activation and clearance of HSCs can be mediated by ligand−receptor interactions. Members of the a disintegrin and metalloprotease (ADAM) family are involved in the proteolytic release of...

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Bibliographic Details
Main Authors: Dirk Schmidt-Arras, Stefan Rose-John
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/10/1226