Targeted Disruption of ALK Reveals a Potential Role in Hypogonadotropic Hypogonadism.

Mice lacking ALK activity have previously been reported to exhibit subtle behavioral phenotypes. In this study of ALK of loss of function mice we present data supporting a role for ALK in hypogonadotropic hypogonadism in male mice. We observed lower level of serum testosterone at P40 in ALK knock-ou...

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Bibliographic Details
Main Authors: Barbara Witek, Abeer El Wakil, Christoffer Nord, Ulf Ahlgren, Maria Eriksson, Emma Vernersson-Lindahl, Åslaug Helland, Oleg A Alexeyev, Bengt Hallberg, Ruth H Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4425494?pdf=render