Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; referees: 2 approved]

Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; referees: 2 approved]

Inflammasomes are high-molecular-weight protein complexes that are formed in the cytosolic compartment in response to danger- or pathogen-associated molecular patterns. These complexes enable activation of an inflammatory protease caspase-1, leading to a cell death process called pyroptosis and to p...

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Bibliographic Details
Main Authors: Tomasz Próchnicki, Matthew S. Mangan, Eicke Latz
Format: Article
Language:English
Published: F1000 Research Ltd 2016-06-01
Series:F1000Research
Subjects:
Cell Growth & Division
Cell Signaling
Chemical Biology of the Cell
Immunity to Infections
Immunomodulation
Immunopharmacology & Hematologic Pharmacology
Innate Immunity
Leukocyte Signaling & Gene Expression
Small Molecule Chemistry
Online Access:http://f1000research.com/articles/5-1469/v1

Internet

http://f1000research.com/articles/5-1469/v1

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