Relating the gut metagenome and metatranscriptome to immunotherapy responses in melanoma patients

Relating the gut metagenome and metatranscriptome to immunotherapy responses in melanoma patients

Abstract Background Recent evidence suggests that immunotherapy efficacy in melanoma is modulated by gut microbiota. Few studies have examined this phenomenon in humans, and none have incorporated metatranscriptomics, important for determining expression of metagenomic functions in the microbial com...

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Bibliographic Details
Main Authors: Brandilyn A. Peters, Melissa Wilson, Una Moran, Anna Pavlick, Allison Izsak, Todd Wechter, Jeffrey S. Weber, Iman Osman, Jiyoung Ahn
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Genome Medicine
Subjects:
Melanoma
Immunotherapy
Microbiome
Metagenome
Metatranscriptome
Online Access:http://link.springer.com/article/10.1186/s13073-019-0672-4

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http://link.springer.com/article/10.1186/s13073-019-0672-4

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