Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation

Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation

The application of current channelrhodopsin-based optogenetic tools is limited by the lack of strict ion selectivity and the inability to extend the spectra sensitivity into the near-infrared (NIR) tissue transmissible range. Here we present an NIR-stimulable optogenetic platform (termed 'Opto-...

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Bibliographic Details
Main Authors: Lian He, Yuanwei Zhang, Guolin Ma, Peng Tan, Zhanjun Li, Shengbing Zang, Xiang Wu, Ji Jing, Shaohai Fang, Lijuan Zhou, Youjun Wang, Yun Huang, Patrick G Hogan, Gang Han, Yubin Zhou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
Optogenetics
Calcium signaling
Nanoparticles
Immune response
Near infrared
STIM1
Online Access:https://elifesciences.org/articles/10024

Internet

https://elifesciences.org/articles/10024

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